RNA Kinetics

The RNAKinetics server is a web interface for the newly developed RNAKinetics software. The software models the dynamics of RNA secondary structure by the means of kinetic analysis of folding transitions of a growing RNA molecule. The result of the modeling is a kinetic ensemble, i.e. a collection of RNA structures that are endowed with probabilities, which depend on time. This approach gives comprehensive probabilistic description of RNA folding pathways, revealing important kinetic details that are not captured by the traditional structure prediction methods.


Ludmila V. Danilova 1, Dmitri D. Pervouchine 2,3,
Alexander V. Favorov 4, and Andrei A. Mironov 2,4.
1 Institute for Information Transmition Problems RAS, Bolshoi Karetnyi per. 19, Moscow, 127994, Russia.
2 Dept. of Bioengineering and Bioinformatics, Moscow State University, Lab. Bldg B, Vorobiovy Gory 1-73, Moscow 119992, Russia.
3 Center for BioDynamics, Boston University, 111 Cummington street, Boston, MA 02215, USA.
4 State Scientific Centre "GosNIIGenetika", 1st Dorozhny pr. 1, Moscow, 117545, Russia.


Danilova, L.V., Pervouchine, D.D., Favorov, A.V., Mironov, A.A. (2006) RNAKinetics: a web server that models secondary structure kinetics of an elongating RNA. J Bioinform Comput Biol 4(2):589-596.

Mail to Ludmila Danilova