SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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SDPsite is a tool for identification of protein active and other functional sites, based on spatial clustering of SDPs (specificity-determining positions, described here) with CPs (conserved positions). The analysis begins with a multiple alignment of a protein family.

Select one of the options:

 Predict SDPs only

 Predict CPs only

 Predict SDPs and CPs

 Map a pre-identified list of SDPs and/or CPs onto a structure