SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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##FAMILY##

This family contains a protein with resolved 3D structure: NRDI_BACSU/4-113, pdb ID: 1rlj. SDPsite predicts following important positions (numbering corresponds to 1rlj):

  • SDPs:

    7D, 51P, 77G, 102S, 55Q, 83S, 98K, 49Q, 79N, 5I, 90Q, 86T, 76W, 84A, 59E, 53S, 62A

  • CPs:

    94P, 72G, 103G, 107D, 73N, 16F, 57F, 61Y, 38F, 12N, 100E, 80F, 99F, 75V, 76W, 6F

  • Best cluster:

    7D, 49Q, 51P, 53S, 55Q, 72G, 73N, 76W, 77G, 79N, 80F, 83S, 84A, 86T, 98K, 99F, 100E, 102S

  • Second best cluster:

    51P, 62A, 38F, 57F, 59E, 61Y, 62A

  • Mapping predictions onto structure of 1rlj:

  • Associated grouping:

    • Group 1

      • Q6E0T2_BORHE/9-119
      • NRDI_STAAR/3-115
      • NRDI_STAEP/3-115
      • NRDI_DEIRA/4-115
      • NRDI_BACSU/4-113
      • NRDIB_BPSPC/1-113
      • Q6HLJ7_BACHK/3-111
    • Group 2

      • NRDI_WIGBR/5-123
      • Q73VB3_MYCPA/9-131
      • Q6NFG8_CORDI/10-129
      • NRDI_MYCGA/21-141
      • Q8E1D8_STRA5/8-127
      • NRDI_STRP8/7-126
      • NRDI_ECOLI/5-123
      • NRDI_CORAM/4-128
      • Q6NFL9_CORDI/4-128
      • NRDI_MYCGE/23-143
      • NRDI_YERPE/5-124
      • NRDI_MYCPN/23-143
      • Q6D1W1_ERWCT/5-124
      • NRDI_MYCPU/23-143
      • Q7N772_PHOLL/7-126
      • Q6F0T6_MESFL/23-143
      • Q6MSC4_MYCMS/23-143
      • NRDI_AGRT5/5-124
      • NRDI_BRUSU/5-123
    • Group 3

      • Q838H6_ENTFA/3-115
      • NRDI_LACLC/3-123
      • Q74HR1_LACJO/4-116
    • Group 4

      • Q834Y6_ENTFA/3-141
      • Q88U55_LACPL/8-146
      • Q8DRF4_STRR6/50-188
      • Q8DSK4_STRMU/7-144
      • Q8DXB0_STRA5/6-140
      • Q8NZA2_STRP8/6-140
      • NRDL_STRP3/6-140