SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: RSN_MOUSE/1-110, pdb ID: 1rfx. SDPsite predicts following important positions (numbering corresponds to 1rfx):

  • SDPs:

    35V, 67A, 80S, 26F, 77T, 49D, 130L, 82G, 82G, 82G, 82G, 82G, 82G, 82G, 79S, 79S, 71I, 73L, 51A, 91T

  • CPs:

    105W, 122W, 75C, 87C, 96C, 98C, 102C, 113C, 115C, 117C, 127C

  • Best cluster:

    49D, 51A, 67A, 71I, 73L, 75C, 77T, 79S, 80S, 82G, 87C

  • Second best cluster:

    35V, 91T

  • Mapping predictions onto structure of 1rfx:

  • Associated grouping:

    • Group 1

      • RSN_HUMAN/1-106
      • RSN_MOUSE/1-110
      • Q8K4J7_RAT/1-110
    • Group 2

      • Q8K425_MOUSE/1-104
      • Q8K426_MOUSE/7-116
      • RSNA_RAT/1-110
      • Q8JZM3_MOUSE/7-116