SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: P96671_BACSU/5-183, pdb ID: 1uxo. SDPsite predicts following important positions (numbering corresponds to 1uxo):

  • SDPs:

    23L, 72L, 122I, 112F, 139I, 100A, 92G, 154A, 124E, 81L, 123I, 22W, 90L, 68V, 80F, 118D, 183S, 121K, 63E, 114Q, 36I, 109L, 115G, 176I, 174L, 108M, 151Q, 28L, 47L, 75P, 113T, 73G, 20F, 20F, 145S, 74C, 55S, 46R

  • CPs:

    19W, 50W, 174L, 18H, 70H, 164H

  • Best cluster:

    23L, 72L, 74C, 80F, 118D, 154A, 164H

  • Second best cluster:

    183S, 19W, 20F, 28L, 46R, 47L, 50W, 68V, 70H, 73G, 75P, 81L, 90L, 109L, 112F, 113T, 121K, 122I, 123I

  • Mapping predictions onto structure of 1uxo:

  • Associated grouping:

    • Group 1

      • Q6F9B1_ACIAD/4-177
      • Q8D657_VIBVU/9-184
      • Q8E8L3_SHEON/4-180
    • Group 2

      • Q7NQ94_CHRVO/9-194
      • Q8XX01_RALSO/5-175
      • Q98JQ9_RHILO/4-172
      • Q7P136_CHRVO/10-177
      • Q9RVS7_DEIRA/12-182
      • Q9A6A9_CAUCR/12-181
      • Q7VYN0_BORPE/5-173
      • Q6FZJ3_BARQU/8-177
      • Q8UAE6_AGRT5/4-173
      • Q8FZZ3_BRUSU/4-173
      • Q9I6T7_PSEAE/8-180
      • Q98NM4_RHILO/8-177
      • Q88CL3_PSEPK/8-180
      • Q87US8_PSESM/8-180
      • Q8G175_BRUSU/8-177
      • Q7CYE5_AGRT5/20-189