SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: YMH9_YEAST/30-180, pdb ID: 1xe7. SDPsite predicts following important positions (numbering corresponds to 1xe7):

  • SDPs:

    146F, 113Y, 143G, 104H, 95F, 147K, 149S, 43R, 159N, 99I, 81L, 166V, 105I, 121Q, 168V, 156E, 115L, 56Y, 123K, 53R, 38Q, 34I, 125F, 87T, 180K, 80T, 78Q, 109G

  • CPs:

    103I, 96H, 169P, 42H, 45G, 46G, 171F, 44E, 76R, 48F, 142P, 101R, 97K, 104H, 170G, 108R, 83Y, 84Y, 82I, 85L

  • Best cluster:

    42H, 43R, 44E, 45G, 46G, 48F, 80T, 81L, 82I, 83Y, 84Y, 85L, 95F, 96H, 97K, 101R, 103I, 104H, 105I, 113Y, 142P, 143G, 146F, 147K, 149S, 166V, 168V, 169P, 170G, 171F

  • Second best cluster:

    108R, 109G

  • Mapping predictions onto structure of 1xe7:

  • Associated grouping:

    • Group 1

      • Q8DN67_STRR6/14-148
      • Q8XJ45_CLOPE/5-144
      • Q8EIN8_SHEON/4-136
      • Q8CTK8_STAEP/4-134
      • Q8NXR1_STAAW/4-136
    • Group 2

      • YMH9_YEAST/30-180
      • Q8GYZ3_ARATH/8-170
      • Q8LDX4_ARATH/8-146
    • Group 3

      • Q9AK66_STRCO/9-144
      • Q9AAS8_CAUCR/14-145
      • Q8G599_BIFLO/12-156
      • Q8U9W0_AGRT5/7-137
      • Q8P808_XANCP/5-140
      • Q8PJF9_XANAC/5-138
      • Q92MF7_RHIME/8-138
      • Q98G01_RHILO/4-138