SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: GLSA2_BACSU/32-327, pdb ID: 1mki. SDPsite predicts following important positions (numbering corresponds to 1mki):

  • SDPs:

    71T, 121F, 94L, 314L, 244K, 217I, 203K, 124M, 272S, 134S, 220I, 145L, 81F, 111R, 245A, 325S, 297I, 191E, 249T, 239V, 102T, 242L, 52C

  • CPs:

    205C, 39P, 201Y, 253Y, 280P, 300P, 37Y, 101P, 32G, 64G, 70F, 107N, 126N, 128G, 177N, 251G, 264G, 273G, 306G, 123P

  • Best cluster:

    71T, 81F, 94L, 101P, 102T, 111R, 121F, 123P, 126N, 128G, 134S, 145L, 191E, 201Y, 203K, 205C, 217I, 239V, 242L, 244K, 245A, 249T, 251G, 253Y, 272S

  • Second best cluster:

    52C, 70F, 273G, 297I, 300P, 314L

  • Mapping predictions onto structure of 1mki:

  • Associated grouping:

    • Group 1

      • GLSA_CAUCR/24-306
      • GLSA_STRCO/25-307
      • GLSA_PSEAE/19-302
      • GLSA_RHIET/22-307
      • GLSA_RHILO/28-313
      • GLSA_VIBCH/22-306
      • GLSA2_ECOLI/24-308
    • Group 2

      • GLSA1_BACHD/22-308
      • GLSA1_BACSU/23-309
      • GLSA2_BACHD/33-324
      • GLSA2_BACSU/32-327
    • Group 3

      • GLS1_CAEEL/171-458
      • GLS2_CAEEL/174-460
      • GLSL_HUMAN/177-463
      • GLSK_HUMAN/244-530