SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: TCMI_STRGA/11-106, pdb ID: 1tuw. SDPsite predicts following important positions (numbering corresponds to 1tuw):

  • SDPs:

    67R, 89D, 48L, 29T, 76N, 19V, 59I, 46H, 22A, 44R, 68S, 47D, 37V, 106A, 80G, 12D, 60M, 105T, 15D, 28T

  • CPs:

    90W, 104W, 51H, 49Y, 86Y, 102Y, 23F, 27D, 36G

  • Best cluster:

    12D, 15D, 19V, 22A, 23F, 44R, 46H, 47D, 48L, 49Y

  • Second best cluster:

    104W, 105T, 106A

  • Mapping predictions onto structure of 1tuw:

  • Associated grouping:

    • Group 1

      • CURG_STRCN/10-106
      • YHB2_STRCO/10-107
      • Q9F6E4_STRCU/10-106
    • Group 2

      • O32461_9ACTO/10-107
      • Q54172_STRFR/10-107
      • Q9ZGD8_STRCY/10-107
    • Group 3

      • Q9FD21_STRCU/10-105
      • Q9L4X9_9ACTO/11-106
      • TCMI_STRGA/11-106