SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: Y227_HAEIN/1-153, pdb ID: 1jop. SDPsite predicts following important positions (numbering corresponds to 1jop):

  • SDPs:

    72Q, 15L, 62A, 148V, 4S, 12K, 136V, 134C, 32N, 54T, 103Q, 75I, 111K, 45I, 2I, 74L, 55A, 133C, 48N, 113T, 131K, 16P, 141E, 123V, 126P, 147V, 60K, 102Y, 80N, 28T, 11F, 42N, 120M, 38R, 135V

  • CPs:

    65H, 130H, 68Y, 37G, 70D, 101D, 145K

  • Best cluster:

    2I, 4S, 111K, 12K, 15L, 16P, 37G, 38R, 45I, 48N, 62A, 65H, 68Y, 70D, 72Q, 74L, 75I, 80N, 101D, 102Y, 103Q, 120M, 123V, 126P, 130H, 131K, 133C, 134C, 145K, 147V, 148V

  • Second best cluster:

    111K, 113T

  • Mapping predictions onto structure of 1jop:

  • Associated grouping:

    • Group 1

      • Q9CLH6_PASMU/1-152
      • YIAL_ECOLI/1-152
      • Q9KRT1_VIBCH/15-167
      • YJGK_ECOLI/1-150
      • YHCH_ECOLI/1-151
      • Y227_HAEIN/1-153
      • Q9CKB2_PASMU/1-153
    • Group 2

      • Q97PE9_STRPN/1-150
      • Q98PQ9_MYCPU/1-152
      • EBGC_ECOLI/1-142
      • Q54723_STRPN/1-150
      • Q97Q98_STRPN/1-150