SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: Q9X0V2_THEMA/4-323, pdb ID: 1vkd. SDPsite predicts following important positions (numbering corresponds to 1vkd):

  • SDPs:

    17P, 280N, 12P, 61R, 278V, 189D, 111K, 116Y, 167M, 76S, 9P, 49V, 260R, 216G, 165Y, 299Y, 78D, 187S

  • CPs:

    107P, 242Y, 268P, 46N, 106D, 276G, 283F, 301G, 304D, 60F

  • Best cluster:

    12P, 46N, 49V, 60F, 61R, 76S, 78D, 106D, 107P, 216G, 278V, 280N, 283F, 299Y, 301G

  • Second best cluster:

    165Y, 187S, 189D

  • Mapping predictions onto structure of 1vkd:

  • Associated grouping:

    • Group 1

      • Q9WZN9_THEMA/15-332
      • Q9YFA2_AERPE/26-361
      • O67215_AQUAE/17-345
    • Group 2

      • Q9X0V2_THEMA/4-323
      • Q9X2G7_THEMA/4-296
      • Q9HH03_PYRFU/31-329
      • Q9UZM0_PYRAB/1-299
      • O58834_PYRHO/1-299