SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: Q9JR91_NEIMA/4-82, pdb ID: 1puz. SDPsite predicts following important positions (numbering corresponds to 1puz):

  • SDPs:

    46F, 14F, 23L, 57L, 35F, 27F, 72L, 12I, 76L, 25L, 69K, 9K, 52F, 47S, 39S, 20L, 13R, 31M

  • CPs:

    60L, 19G, 54D, 30F, 18R, 22E

  • Best cluster:

    12I, 13R, 18R, 19G, 20L, 22E, 23L, 25L, 27F, 30F, 31M, 35F, 46F, 54D, 57L

  • Second best cluster:

    52F, 60L, 69K, 72L, 76L

  • Mapping predictions onto structure of 1puz:

  • Associated grouping:

    • Group 1

      • Q9JR91_NEIMA/4-82
      • Q9PEF4_XYLFA/17-95
      • Q9I5G9_PSEAE/2-83
      • YGFY_ECOLI/1-82
      • Q9KPA2_VIBCH/2-83
      • YGFY_HAEIN/1-82
      • Q9CK44_PASMU/1-82
    • Group 2

      • Q9A781_CAUCR/24-105
      • Q98LX8_RHILO/10-92
      • Q9AKD4_RICTY/5-87
      • Q9CYQ2_MOUSE/60-144
      • Q9V5L2_DROME/60-144
      • YDE6_SCHPO/44-127
      • Q08230_YEAST/61-147