SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: RECU_BACSU/30-196, pdb ID: 1rzn. SDPsite predicts following important positions (numbering corresponds to 1rzn):

  • SDPs:

    42N, 188Y, 184P, 129Q, 77E, 46L, 132I, 54H, 78A, 53I, 116H, 106N, 52V, 123M, 185R, 103E, 133C, 105K, 120I, 57P, 91I, 152F, 193E, 47T, 172E, 176Y, 154F, 128A, 126V, 194Q, 168K, 40E, 114N

  • CPs:

    118H, 88Y, 31G, 87D, 90G, 94G, 99F, 134F, 59P, 92Y, 122H, 32M, 35E, 55K, 102K, 119Q

  • Best cluster:

    42N, 52V, 53I, 54H, 55K, 87D, 88Y, 90G, 91I, 92Y, 99F, 132I, 133C, 134F, 188Y

  • Second best cluster:

    118H, 119Q, 120I, 122H, 123M

  • Mapping predictions onto structure of 1rzn:

  • Associated grouping:

    • Group 1

      • Q9K734_BACHD/7-167
      • RECU_STAAW/31-199
      • RECU_BACHD/29-196
      • RECU_BACSU/30-196
      • Q9EXN0_ENTHR/33-201
      • Q9EXN2_ENTFA/33-201
      • RECU_LACLA/43-209
      • RECU_STROR/25-191
      • RECU_STRPY/26-192
    • Group 2

      • RECU_MYCPU/5-154
      • RECU_UREPA/5-163
      • RECU_MYCGE/5-163