SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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##FAMILY##

This family contains a protein with resolved 3D structure: Y986_PYRHO/2-243, pdb ID: 1v6t. SDPsite predicts following important positions (numbering corresponds to 1v6t):

  • SDPs:

    117A, 161A, 70G, 68L, 164V, 74R, 4D, 30S, 147S, 69M, 7S, 125A, 162H, 146N, 222V, 158L, 140I, 75Y, 83A, 85N, 12S, 154E, 42P, 53K, 199M, 78L, 128V, 55N, 51L, 211E, 189K, 130E, 98A, 105L, 29T, 235Y, 200V, 187E, 160V, 91V, 66P, 84R, 193A, 180G, 201K, 47K, 171N, 195R, 81E, 81E

  • CPs:

    38H, 111H, 221C, 89Y, 115Y, 223H, 35C, 170Y, 62H, 6N, 8D, 21D, 32N, 60G, 67D, 71F, 72G, 112G

  • Best cluster:

    68L, 70G, 83A, 32N, 38H, 62H, 67D, 68L, 69M, 70G, 71F, 72G, 111H, 112G, 221C, 222V, 223H

  • Second best cluster:

    4D, 29T, 30S, 60G, 81E, 83A, 84R, 85N, 89Y, 91V, 105L, 115Y, 125A, 128V, 130E, 140I, 146N, 147S, 158L, 160V, 161A, 162H

  • Mapping predictions onto structure of 1v6t:

  • Associated grouping:

    • Group 1

      • Y1821_BACHD/3-244
      • Y1605_STAAM/2-243
      • Y986_PYRHO/2-243
      • Y1541_CAMJE/3-244
    • Group 2

      • YBGL_ECOLI/2-238
      • Y1729_HAEIN/3-239
      • Y030_NEIMA/3-239
    • Group 3

      • Y333_MYCLE/3-244
      • Y441_STRCO/1-242
      • Y2984_DEIRA/6-249
      • Y492_PSEAE/3-244
    • Group 4

      • Y3576_VIBCH/5-246
      • Y2112_PSEAE/3-247
      • Y4511_PSEAE/7-251