SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: GLPX_ECOLI/2-322, pdb ID: 1ni9. SDPsite predicts following important positions (numbering corresponds to 1ni9):

  • SDPs:

    183A, 305T, 307L, 135L, 192S, 164K, 294I, 185P, 95M, 169A, 206Y, 139L, 28D, 199D, 227D, 274R, 60I, 175Q, 258A, 310G, 92M, 151G, 320S, 194L, 44L, 269L, 154L, 177L, 137L

  • CPs:

    322H, 64P, 86P, 119Y, 212P, 23W, 25G, 27G, 33D, 56G, 58G, 61D, 69G, 73G, 85D, 89G, 96G, 134D, 142N, 178G, 186D, 187G, 188D, 209G, 214G, 226G, 260G, 280F, 284G, 288G

  • Best cluster:

    164K, 183A, 185P, 186D, 187G, 188D, 192S, 194L, 206Y

  • Second best cluster:

    134D, 135L, 137L, 139L, 142N, 154L, 175Q, 177L, 178G

  • Mapping predictions onto structure of 1ni9:

  • Associated grouping:

    • Group 1

      • YGGF_ECOLI/1-321
      • GLPX_HAEIN/2-322
      • GLPX_ECOLI/2-322
    • Group 2

      • YWJI_BACSU/2-309
      • Q9X788_MYCLE/23-331
      • P96017_9SYNC/2-334