SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: SUFE_ECOLI/10-135, pdb ID: 1mzg. SDPsite predicts following important positions (numbering corresponds to 1mzg):

  • SDPs:

    35P, 130I, 56W, 84V, 20W, 123L, 22E, 39D, 125A, 21E, 37L, 15L, 47S, 68E, 102V, 100F, 90D, 34L, 34L, 34L, 34L, 23K, 28I, 28I, 25L, 25L, 25L, 25L

  • CPs:

    51C, 80G, 122G, 119R, 24Y, 14F, 56W, 50G, 69L, 106F, 48I

  • Best cluster:

    20W, 21E, 22E, 23K, 24Y, 25L

  • Second best cluster:

    34L, 35P, 37L, 47S, 48I, 50G, 51C, 56W, 68E, 69L, 80G, 84V, 119R, 122G, 123L, 125A, 130I

  • Mapping predictions onto structure of 1mzg:

  • Associated grouping:

    • Group 1

      • SUFE_ECOLI/10-135
      • Y1293_HAEIN/1-126
      • Y3312_MYCBO/14-140
      • YGDK_ECOLI/20-145
    • Group 2

      • Y1419_SYNY3/25-148
      • O84327_CHLTR/20-141
      • Q9Z9B0_CHLPN/20-141