SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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##FAMILY##

This family contains a protein with resolved 3D structure: YCHN_ECOLI/2-117, pdb ID: 1jx7. SDPsite predicts following important positions (numbering corresponds to 1jx7):

  • SDPs:

    83-, 20N, 21S, 67I, 101L, 8A, 100T, 84G, 31Q, 83-, 49G, 87I, 22L, 32E, 11A, 26I, 104L, 47T, 47T, 42M, 83-, 60N, 53Q, 97E, 73V, 85R, 75V

  • CPs:

    81C, 86G, 45A, 40F

  • Best cluster:

    83-, 21S, 22L, 40F, 45A, 47T, 49G, 75V, 81C, 83-, 84G, 85R, 86G, 87I, 97E, 100T, 101L, 104L

  • Second best cluster:

    31Q, 32E

  • Mapping predictions onto structure of 1jx7:

  • Associated grouping:

    • Group 1

      • Q9X076_THEMA/1-116
      • DSRE_CHRVI/1-128
      • Y2605_PSEAE/1-127
      • YHEN_ECOLI/1-128
      • Y1351_PASMU/1-126
      • Y576_HAEIN/1-126
      • Y356_VIBCH/4-131
      • Y532_BUCAI/1-128
    • Group 2

      • O30051_ARCFU/2-119
      • Y760_METJA/157-275
      • O27468_METTH/151-269
    • Group 3

      • DSRF_CHRVI/6-136
      • Y2606_PSEAE/3-119
      • Y1352_PASMU/1-119
      • YHEM_HAEIN/1-119
      • Y357_VIBCH/2-118
      • YHEM_ECOLI/2-119
      • Y531_BUCAI/2-119