SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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##FAMILY##

This family contains a protein with resolved 3D structure: Y637_METTH/10-85, pdb ID: 1jrm. SDPsite predicts following important positions (numbering corresponds to 1jrm):

  • SDPs:

    40E, 59E, 65G, 78Q, 72S, 20V, 32Y, 21S, 84Q, 46P, 82R, 52A, 55E, 39I

  • CPs:

    53N, 73G, 22P, 50G

  • Best cluster:

    20V, 21S, 22P, 52A, 53N, 55E, 59E

  • Second best cluster:

    32Y, 39I, 40E, 72S, 73G, 78Q

  • Mapping predictions onto structure of 1jrm:

  • Associated grouping:

    • Group 1

      • Q8IKR0_PLAF7/24-101
      • Q8GWQ6_ARATH/140-216
      • U235_HUMAN/32-108
      • Q9VZT2_DROME/46-122
    • Group 2

      • Y273_METKA/8-83
      • Y618_METJA/9-84
      • Y1765_PYRFU/5-80
      • Y501_PYRAB/5-80
      • Y637_METTH/10-85
      • Y822_METMA/13-92
      • Y2072_ARCFU/4-77
    • Group 3

      • Y1994_SYNEL/3-74
      • Y1301_RICCN/10-90
      • Y3196_ANASP/2-73
      • Y1736_LEPIN/1-73
      • Y182_AERPE/20-95
    • Group 4

      • Y1832_CHLTE/7-83
      • Y1313_PASMU/10-86
      • Q8VJT0_MYCTU/1-76
      • Q44934_BARBA/8-89
      • Y3356_SHEON/7-83
      • Y388_CHLTR/17-93
      • Y497_CHLPN/1-77
      • Y3622_CAUCR/3-84
      • YGGU_ECOLI/7-83
      • Y2660_AGRT5/17-98
      • Y4154_RHILO/8-89
      • Y458_VIBCH/7-83
      • Y2619_VIBPA/8-84