SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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##FAMILY##

This family contains a protein with resolved 3D structure: Y844_THEMA/1-150, pdb ID: 1o6d. SDPsite predicts following important positions (numbering corresponds to 1o6d):

  • SDPs:

    14F, 12D, 102P, 15I, 124F, 11L, 129T, 103Y, 39R, 11-, 10K, 19I, 13G, 29F, 141F, 71K

  • CPs:

    150H, 126H, 149Y, 22Y, 138F, 104G, 100G, 135E, 139R, 73G, 52E

  • Best cluster:

    102P, 11L, 12D, 13G, 14F, 15I, 19I, 39R, 100G, 102P, 103Y, 104G, 124F, 126H, 129T

  • Second best cluster:

    22Y, 29F, 135E, 138F, 139R, 141F

  • Mapping predictions onto structure of 1o6d:

  • Associated grouping:

    • Group 1

      • Y1113_ACIAD/1-157
      • Y2195_RALSO/1-154
      • Y418_NEIMA/1-154
      • Y2605_YERPE/1-154
      • Y4004_PSEAE/1-154
      • Y2613_XANCP/1-154
      • Y338_XYLFA/2-155
    • Group 2

      • Y3433_CAUCR/2-153
      • Y211_BRUME/1-172
      • Y4004_RHILO/1-158
      • Y2776_AGRT5/1-158
      • Y3164_RHIME/1-158
    • Group 3

      • Y180_UREPA/1-158
      • YWAE_LACLA/1-158
      • Y254_MYCPU/1-144
      • Y463_FUSNN/1-154
      • Y2600_CLOPE/1-158
      • Y3536_CLOAB/1-158
      • Y247_DESTE/1-158
      • Y2238_STRPN/1-158
      • Y1863_STRP3/1-158
      • YORX_STAHO/1-158
      • Y4007_BACHD/1-158
      • YYDA_BACSU/1-158
      • Y321_LISIN/1-158