SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: MAF_BACSU/3-188, pdb ID: 1ex2. SDPsite predicts following important positions (numbering corresponds to 1ex2):

  • SDPs:

    13R, 168Y

  • CPs:

    142Y, 72D, 153G, 178G, 14R, 34E, 85K, 108T, 170G, 86P, 130F, 7L, 9S, 11S, 18L

  • Best cluster:

    72D, 9S, 11S, 13R, 142Y, 18L

  • Second best cluster:

    85K, 86P

  • Mapping predictions onto structure of 1ex2:

  • Associated grouping:

    • Group 1

      • Y815_RICPR/8-212
      • YCEF_ECOLI/2-192
      • Y1161_HELPJ/1-189
      • Y3282_MYCTU/3-210
      • Y905_SYNY3/3-195
    • Group 2

      • Y1941_PYRHO/2-186
      • Y1718_AQUAE/1-189
      • YHDE_ECOLI/3-192
      • MAF_BACSU/3-188
      • YOZ1_YEAST/19-231
      • Y022_CHLPN/3-195
      • Y349_CHLTR/3-195