SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: RPIB_ECOLI/62-142, pdb ID: 1nn4. SDPsite predicts following important positions (numbering corresponds to 1nn4):

  • SDPs:

    133R, 134H, 99H, 137R, 130E, 63I, 107F, 102T, 78K, 141I, 106A, 98Q, 125L, 115E, 97R, 64L, 82I

  • CPs:

    69G, 71G, 66C, 62G, 77N, 81G, 93A, 120I, 124W

  • Best cluster:

    62G, 63I, 64L, 77N, 78K, 81G, 82I, 93A, 97R, 98Q, 99H, 102T, 106A, 107F, 120I, 124W, 125L, 130E, 133R, 134H, 137R, 141I

  • Second best cluster:

    66C, 69G, 71G

  • Mapping predictions onto structure of 1nn4:

  • Associated grouping:

    • Group 1

      • P74234_SYNY3/9-88
      • LACB_STRMU/61-142
      • LACB_LACLA/61-142
    • Group 2

      • Q9ZB26_BRUAB/61-142
      • YWLF_BACSU/62-142
      • RPIB_ECOLI/62-142
      • LACA_LACLA/58-138
      • Y396_MYCGE/65-145
      • Q9ZDM8_RICPR/64-144
      • O86950_THENE/61-141
      • O25298_HELPY/66-146
      • O67211_AQUAE/61-141