SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: Y065_HAEIN/14-141, pdb ID: 1fl9. SDPsite predicts following important positions (numbering corresponds to 1fl9):

  • SDPs:

    97F, 71V, 84F, 72E, 102D, 49L, 54L, 140I, 62N, 136D, 69T, 105N, 14M, 103Y, 67T, 32K, 98M, 126D, 141E, 18G

  • CPs:

    116W, 84H, 66P, 88Y, 40G, 45G, 86D, 43G, 74Y, 46K, 47T

  • Best cluster:

    45G, 46K, 47T, 49L, 54L, 66P, 67T, 69T, 71V, 72E, 74Y, 84F, 86D, 97F, 98M, 102D, 103Y

  • Second best cluster:

    140I, 141E

  • Mapping predictions onto structure of 1fl9:

  • Associated grouping:

    • Group 1

      • O25418_HELPY/6-128
      • YDIB_BACSU/14-134
      • Y875_TREPA/11-132
      • Y013_RICPR/10-132
      • O84542_CHLTR/14-140
      • Q9Z7P7_CHLPN/14-136
    • Group 2

      • Y2300_ANASP/22-146
      • Y257_SYNY3/16-140
      • Y186_BORBU/11-134
      • Y843_AQUAE/15-128
      • YJEE_ECOLI/14-136
      • Y065_HAEIN/14-141
      • Y4747_STRCO/1-125
      • Y377_MYCLE/19-149
      • Y3456_MYCBO/30-160