SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: PTH_ARCFU/12-100, pdb ID: 1rzw. SDPsite predicts following important positions (numbering corresponds to 1rzw):

  • SDPs:

    71L, 28A, 16S, 30I, 76G, 53L, 66H, 83L, 45D, 85E, 98P, 86V, 37S, 100E, 34K, 69E, 65K, 46E, 77L, 77L

  • CPs:

    43W, 26H, 18G

  • Best cluster:

    26H, 28A, 30I, 34K, 37S, 43W, 45D, 46E, 65K, 66H, 69E, 76G, 77L, 85E, 86V, 98P

  • Second best cluster:

    16S, 18G

  • Mapping predictions onto structure of 1rzw:

  • Associated grouping:

    • Group 1

      • PTH_METJA/10-101
      • PTH_METTH/10-98
      • O82633_ARATH/88-181
      • PTH2_CAEEL/210-302
    • Group 2

      • O69834_STRCO/163-244
      • PTH_PYRHO/16-107
      • PTH_ARCFU/12-100
      • PTH2_YEAST/103-200
      • PTH2_SCHPO/100-191