SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: IF6_METJA/5-207, pdb ID: 1g61. SDPsite predicts following important positions (numbering corresponds to 1g61):

  • SDPs:

    2121S, 2147L, 2204S, 2199C, 2202A, 2157T, 2026T, 2089K, 2153N, 2127F, 2174F, 2128K, 2191K, 2021T, 2077E, 2149T, 2025I, 2113T, 2182E, 2023E, 2184I, 2180K, 2090E, 2082D, 2041S, 2156V, 2117G, 2087F, 2193T, 2028L, 2049L, 2186K

  • CPs:

    2016G, 2061G, 2067N, 2109G, 2110N, 2115N, 2152G, 2188G, 2191N, 2193G

  • Best cluster:

    2021T, 2023E, 2025I, 2026T, 2028L, 2049L, 2087F, 2089K, 2090E, 2156V, 2157T, 2202A, 2204S

  • Second best cluster:

    2109G, 2110N, 2113T, 2117G, 2121S, 2127F, 2128K, 2147L, 2149T, 2152G, 2153N

  • Mapping predictions onto structure of 1g61:

  • Associated grouping:

    • Group 1

      • IF6_METJA/5-207
      • IF6_PYRHO/4-206
      • IF6_METTH/3-199
    • Group 2

      • IF6_ARATH/3-206
      • IF6_YEAST/3-204
      • IF6_CAEEL/3-204
      • IF6_DROME/3-204