SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: ECM15_YEAST/6-99, pdb ID: 1lxj. SDPsite predicts following important positions (numbering corresponds to 1lxj):

  • SDPs:

    64H, 86D, 62E, 85T, 21S, 83T, 43H, 49I, 20A, 37P, 60I, 46G, 46G, 87K, 13V, 77T, 68H, 8A, 11C, 78D, 67G, 27A

  • CPs:

    14P, 47T

  • Best cluster:

    86D, 11C, 13V, 14P, 46G, 47T, 49I, 60I, 62E, 64H, 67G, 68H, 77T, 78D

  • Second best cluster:

    85T, 86D, 87K

  • Mapping predictions onto structure of 1lxj:

  • Associated grouping:

    • Group 1

      • Y1052_METJA/7-98
      • Y1187_METTH/2-96
      • O59567_PYRHO/6-98
      • Y230_SYNY3/23-115
      • ECM15_YEAST/6-99
      • YQGV_BACSU/2-90
      • DGLA_STAXY/2-99
    • Group 2

      • O29684_ARCFU/1-93
      • Y1503_CLOPE/4-95
      • O67847_AQUAE/48-140
      • Y1933_MYCBO/3-95