SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: PCRB_BACSU/2-226, pdb ID: 1viz. SDPsite predicts following important positions (numbering corresponds to 1viz):

  • SDPs:

    212Y, 65E, 82P, 115A, 185Y, 155P, 153Q, 146A, 146A, 12K, 116E, 131T, 78L, 67S, 122N, 184F, 128A, 207V, 21D, 71A, 30S, 170A, 84V, 7W, 111E, 164V, 75G, 136D, 44T, 154L, 140D, 99K, 166G, 124D, 145Y, 101M, 63V, 74P, 73V

  • CPs:

    15P, 61P, 118Y, 158Y, 14D, 33D, 39G, 77D, 80F, 86N, 163G, 186G, 187G, 188G, 203D, 208G

  • Best cluster:

    78L, 12K, 63V, 65E, 67S, 73V, 74P, 75G, 78L, 80F, 82P, 84V, 115A, 116E, 118Y, 145Y, 146A, 153Q, 154L, 155P, 158Y, 184F, 185Y

  • Second best cluster:

    122N, 124D, 128A, 163G, 164V, 166G, 186G, 187G, 188G

  • Mapping predictions onto structure of 1viz:

  • Associated grouping:

    • Group 1

      • PCRB_ARCFU/1-230
      • PCRB_STAAU/2-223
      • PCRB_BACSU/2-226
    • Group 2

      • PCRB_METJA/13-246
      • PCRB_PYRHO/14-249
      • PCRB_METTH/11-245