SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: Q9WYV7_THEMA/8-83, pdb ID: 1uwd. SDPsite predicts following important positions (numbering corresponds to 1uwd):

  • SDPs:

    32L, 24G, 48M, 10D, 34Y, 18V, 25L, 57L, 50M, 13N, 26D, 31G, 17N, 72I, 68A, 27V, 33V

  • CPs:

    55C, 20D, 21F, 51T, 22E, 31G, 80V, 18V, 56P, 33V, 30L

  • Best cluster:

    18V, 20D, 21F, 22E, 24G, 25L, 26D, 27V, 30L, 31G, 32L, 33V, 48M, 50M, 51T, 55C, 56P, 57L

  • Second best cluster:

    10D, 13N, 17N, 68A, 72I

  • Mapping predictions onto structure of 1uwd:

  • Associated grouping:

    • Group 1

      • PAAD_ECOLI/13-87
      • Q9RRV2_DEIRA/14-88
      • U195_DROME/35-114
      • U195_CAEEL/37-118
    • Group 2

      • O27700_METTH/16-93
      • Y1129_METJA/3-78
      • O58049_PYRHO/79-154
      • Q9WYV7_THEMA/8-83
      • O33779_SULSO/13-88
      • Q9YAG0_AERPE/21-100
      • O06451_STRPN/11-87
      • O53157_MYCTU/11-89
      • P70949_BACSU/5-80
    • Group 3

      • MRP_SYNY3/3-77
      • MRP_DEIRA/1-75
      • Q9S2E2_STRCO/6-82
      • MRP_MYCLE/11-86
      • MRP_MYCTU/9-84