SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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##FAMILY##

This family contains a protein with resolved 3D structure: NTPA_METJA/11-189, pdb ID: 1b78. SDPsite predicts following important positions (numbering corresponds to 1b78):

  • SDPs:

    185F, 72E, 50L, 47Q, 13F, 130F, 101I, 97G, 106E, 103K, 53V, 71V, 35E, 98N, 95T, 77F, 46I, 43Y, 104L, 93Q, 96I

  • CPs:

    177H, 85P, 17N, 73D, 86G, 132G, 136G, 149F, 152D, 155F, 88Y, 151Y, 20K, 23E, 172K

  • Best cluster:

    93Q, 95T, 96I, 97G, 98N, 101I, 103K, 104L

  • Second best cluster:

    43Y, 46I, 47Q, 53V, 71V, 72E

  • Mapping predictions onto structure of 1b78:

  • Associated grouping:

    • Group 1

      • HAM1_YEAST/6-192
      • NTPA_METJA/11-189
      • O27475_METTH/3-180
      • O28046_ARCFU/1-176
      • O59580_PYRHO/3-180
    • Group 2

      • HAM1_BACSU/7-196
      • HAM1_MYCLE/7-201
      • HAM1_ECOLI/4-194
      • HAM1_HAEIN/5-195