SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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##FAMILY##

This family contains a protein with resolved 3D structure: Y1575_AQUAE/5-239, pdb ID: 1lfp. SDPsite predicts following important positions (numbering corresponds to 1lfp):

  • SDPs:

    128G, 225L, 231V, 69A, 7W, 5S, 18D, 14K, 221L, 160G, 121G, 132Y, 162E, 136R, 123N, 9Q, 175T, 114R, 93G, 150E, 32I, 214T, 148S, 6H, 78E, 120H, 204I, 143P, 190L, 133L, 235I, 95V, 130V, 229D, 79G, 62P, 205S, 97V, 12H, 126A, 124L, 169E, 35A, 216Q, 39G, 56A, 41P, 25F

  • CPs:

    87Y, 46N, 134F, 105N, 94G, 39G, 237N, 230D, 122G, 104D, 203P, 138G, 163D, 108R, 88E, 103T, 121G, 18D, 229D, 62P, 49L, 235I, 14K, 150E, 119K, 42N, 35A, 66I

  • Best cluster:

    87Y, 88E, 93G, 94G, 95V, 97V, 120H, 121G, 122G, 123N, 124L, 126A, 128G, 130V, 132Y, 133L, 134F, 203P, 204I, 205S, 221L, 225L, 235I, 237N

  • Second best cluster:

    103T, 104D, 105N, 108R, 229D, 230D, 231V

  • Mapping predictions onto structure of 1lfp:

  • Associated grouping:

    • Group 1

      • YB30_ARATH/86-331
      • O43075_SCHPO/33-283
      • YG1D_YEAST/30-288
      • Y1135_THETN/5-239
      • Y455_RICPR/5-240
      • Y573_CHLPN/5-238
      • Y457_CHLTR/5-238
      • YU82_CLOHI/5-239
      • Y1570_LISIN/5-239
      • YRBC_BACSU/5-239
      • Y2753_RHIME/5-237
      • Y3243_CAUCR/5-241
      • Y162_HELPY/3-240
      • Y1172_CAMJE/3-235
      • Y2806_VIBCH/3-237
      • Y1661_FUSNN/5-239
      • Y466_THEMA/5-238
      • Y1575_AQUAE/5-239
      • Y2295_CLOAB/5-239
      • Y1954_CLOPE/5-238
      • YEEI_BACSU/3-236
      • Y388_LISIN/3-236
      • YEEN_SALTY/3-236
      • Y1922_STRPN/3-236
      • Y474_TREPA/5-238
      • Y025_BORBU/5-237
      • Y2548_DEIRA/5-237
      • Y1665_CHLTE/5-239
      • Q9S4S9_LEGPN/5-237
      • Y989_SYNY3/4-243
      • Y4276_ANASP/5-241
      • Y1663_CORGL/5-239
      • Y964_PSEAE/5-238
      • Y3027_XANCP/6-236
      • Y1906_XYLFA/6-237
      • Y2190_RALSO/5-238
      • Y1902_NEIMA/5-238
      • Y2635_MYCBO/5-239
      • Y1521_STRCO/5-239
      • Y2055_YERPE/5-238
      • Y315_HAEIN/5-237
    • Group 2

      • Y295_UREPA/2-233
      • Y332_MYCPN/2-235
      • Y332_MYCGE/2-235