SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: MHPD_ECOLI/3-221, pdb ID: 1sv6. SDPsite predicts following important positions (numbering corresponds to 1sv6):

  • SDPs:

    45N, 59R, 40A, 114R, 81T, 44I, 63L, 205L, 29L, 27R, 200C, 17A, 147W, 153D, 154T, 149I, 71Q, 55R, 106A, 72L, 140V, 49D, 54R, 46V, 137L, 216A, 12D, 144I, 152V, 151F, 85D, 14R, 124D, 122T, 126L, 33D, 183M, 101Q, 123F, 210W, 25P, 42Q, 111V, 209V, 79F, 68V, 86M, 18E

  • CPs:

    102P, 204P, 39Y, 53G, 62G, 80G, 157D, 158N, 177D, 195G, 77P

  • Best cluster:

  • Second best cluster:

  • Mapping predictions onto structure of 1sv6:

  • Associated grouping:

    • Group 1

      • O07067_BURCE/5-233
      • DMPH_PSEUF/7-225
      • O24834_ACISP/11-229
    • Group 2

      • Q51981_PSEPU/1-223
      • MHPD_ECOLI/3-221
      • O34721_9SPHN/5-223
      • Q52433_PSESP/9-227
    • Group 3

      • O24831_ACISP/3-222
      • XYLJ_PSEPU/3-222
      • O51854_PSEPU/3-221
      • Q52038_PSEPS/3-221