SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: MPAP6_PHLPR/1-132, pdb ID: 1nlx. SDPsite predicts following important positions (numbering corresponds to 1nlx):

  • SDPs:

    508F, 471L, 475V, 470N, 511H, 435D, 422-, 422G, 477K, 464T, 401M, 401M, 401M, 401M, 401M, 401M, 401M, 401M, 401M, 422-, 419T, 491A, 460E, 449N

  • CPs:

    493Y, 457K, 524E, 506E, 486D, 403A, 525V, 502E, 521G, 501P, 509V, 498H, 528V

  • Best cluster:

    419T, 435D, 460E, 464T, 470N, 471L, 475V, 486D, 491A, 493Y, 498H, 501P, 502E

  • Second best cluster:

    449N, 457K

  • Mapping predictions onto structure of 1nlx:

  • Associated grouping:

    • Group 1

      • MPA5B_LOLPR/7-177
      • O04828_HORVU/8-182
      • MPA91_POAPR/42-237
    • Group 2

      • MPA52_PHAAQ/7-157
      • MPAP6_PHLPR/1-132
      • MPA51_PHAAQ/7-147
      • MPA53_PHAAQ/7-142