SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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##FAMILY##

This family contains a protein with resolved 3D structure: SUFD_ECOLI/163-393, pdb ID: 1vh4. SDPsite predicts following important positions (numbering corresponds to 1vh4):

  • SDPs:

    280E, 219A, 302K, 290H, 187E, 229A, 231N, 297S, 288L, 284T, 327D, 250G, 171Y, 175L, 313F, 365G, 252V, 243S, 223P, 287W, 245S, 261L, 300L, 172R, 344D, 244H, 217K, 391Y, 278K, 263G, 343V, 283D, 323A, 240T, 164E, 228F, 370E, 215H, 299Q, 226H, 335L, 257T, 264E, 234L, 351I, 265N, 325K, 321Q, 389I, 282C, 333N, 326T, 329Q, 185V, 314N, 242F

  • CPs:

    347P, 360H, 379G, 189F, 332N, 199T, 392A, 393F, 378R, 362A, 283D, 374Y

  • Best cluster:

    215H, 217K, 231N, 242F, 243S, 244H, 245S, 257T, 282C, 283D, 284T, 287W, 288L, 299Q, 300L, 302K, 313F, 314N, 332N, 333N

  • Second best cluster:

    261L, 263G, 264E, 265N, 290H, 297S, 323A, 325K, 326T, 327D

  • Mapping predictions onto structure of 1vh4:

  • Associated grouping:

    • Group 1

      • O32165_BACSU/178-411
      • Y076_SYNY3/188-427
      • SUFD_ECOLI/163-393
      • Y593_MYCLE/608-840
      • O32162_BACSU/204-436
      • Q25799_PLAFA/202-441
      • SUFB_ECOLI/227-466
      • Y074_SYNY3/211-451
      • YCF24_PORPU/218-458
      • YCF24_ODOSI/217-457
    • Group 2

      • YB50_METTW/152-383
      • Y2365_ARCFU/114-341
      • Y883_PYRHO/93-322
      • Y034_METJA/81-312