SDPsite: prediction of protein active and specific recognition sites from sequence and structure

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This family contains a protein with resolved 3D structure: EF1B_METTH/1-88, pdb ID: 1gh8. SDPsite predicts following important positions (numbering corresponds to 1gh8):

  • SDPs:

    50A, 81E, 10V, 11M, 62G, 7T, 78S, 87R, 34T, 1M, 26I

  • CPs:

    48G, 44P, 47F, 60D, 9K, 81V, 11M, 85E, 4V, 71E, 77E, 33G, 67E, 18D, 26I, 8I

  • Best cluster:

    7T, 81E, 9K, 10V, 11M, 50A, 78S

  • Second best cluster:

    48G, 33G, 34T, 60D, 62G, 87R

  • Mapping predictions onto structure of 1gh8:

  • Associated grouping:

    • Group 1

      • O15618_ENTHI/36-121
      • EF1B_CANAL/127-213
      • EF1B_SCHPO/128-214
      • O18681_SPHGR/159-245
      • EF1B_ARTSA/120-206
      • EF1D_ARTSA/151-237
      • EF1B_TRYCR/136-222
      • EF1B_RABIT/138-224
      • EF1B_BETVU/141-230
      • EF1B2_WHEAT/128-215
    • Group 2

      • EF1B_ARCFU/1-88
      • EF1B_METJA/1-89
      • EF1B_SULSO/1-88
      • EF1B_METTH/1-88